EP.372/ Evidence-Based Nutrients for PMS, PMDD, Endo Pain and ADHD, and the Gap Between Nutrition Research and Medicine with Alice van der Schoot of Ditto

As some of you may well know, the majority of my clients are complex cases - living with not just endometriosis, but co-conditions such as PMDD, and ADHD. Even those who don’t have these conditions, often come to me plagued with significant PMS symptoms, on top of their endo ones.

And with people with endo being at higher risk of early and premature menopause, I am also seeing clients in their late 30s coming to me with worsening symptoms of these co-conditions (like PMDD and ADHD), which tend to worsen as hormones start to fluctuate in perimenopause.

And it’s why I started being drawn to DITTO, which address not just endo, but ADHD, PMDD, PMS and perimenopause, and I can honestly say the improvements I have seen in my clients, and what they have shared with me themselves, is that DITTO has been life changing for them.

I think so, so many of us are struggling alone out there, with our endo, of course, but with all of these conditions mixed up with it, and so that’s why today on the show, I am interviewing DITTO founder Alice van der Schoot.

And before we get into this episode, I want to reassure you that this isn’t a sponsored episode, I haven’t been paid to have Alice on because she’s a brand. In fact, we’ve been trying to arrange this interview since August, and as you know, I’ve only just become an affiliate of DITTO, after what I’ve been seeing in clients, so this episode was arranged long before I had any affiliate connection. I just wanted to make that clear as I know some people may decide not to listen to the episode if they think the whole thing is an ad, and I don’t want people to miss out on this interview because Alice has so much knowledge to share with us, not just about the specific research and ingredients she uses, but on the challenges we’re facing in terms of nutrition research, gynaecological health and the medical world.

Alice is a PhD nutrition scientist with a background in neuroscience. Her work brings together both fields to explore how nutrition can impact underlying mechanisms of PMS, PMDD, and period pain to reduce symptoms - from neurotransmitter function, to pain processing and inflammation.

Recognising that valuable research often remains hidden in academic journals, Alice founded DITTO to address the disconnect between scientific evidence and meaningful solutions in menstrual health. DITTO has a clinically studied supplement formulated specifically for PMS, PMDD, and period pain, with key nutrients that may also support individuals with endometriosis. DITTO's social channels are also a platform for science communication - breaking down important research to make it accessible to those who need it most, and if you haven’t checked out her Instagram to see her coverage on research, I highly recommend you do!

Okay, so let’s get to the episode!

DITTO links

  • Website

  • Instagram @ditto.daily

  • 20% discount code: ENDOBELLY

Affiliate Partnerships

DITTO - DITTO is a clinically studied PMS and PMDD supplement with 10 ingredients that target both the mental and physical challenges that come along with the menstrual cycle, developed by a PhD Nutrition Scientist. You can use the code: ENDOBELLY (all caps) for 20% off any and all orders, now and in the future.

Mira - Mira is an at-home hormone testing device for every day use. Use this link and code 2DJESS20 to get 20% off the device and any future wand orders.

Tempdrop - Track fertility effortlessly with Tempdrop’s Wearable Sensor. Get 15% off with code: ENDOLIFE

Need more help or want to learn how to work with me?

Ways to work with me:

⁠One to one coaching info and application⁠

Live and Thrive with Endo 2.0 DIY online course

Endo Sessions: Single and mini-package one to one endo coaching

SIBO Sessions: Single and mini-package one to one SIBO coaching

⁠Masterclasses in endo nutrition, surgery prep and recovery and pain relief⁠

⁠This EndoLife, It Starts with Breakfast digital cookbook⁠

Free resources:

This podcast! 

⁠Endometriosis Net Column⁠

⁠Endometriosis News Column⁠

⁠Substack ⁠

⁠Instagram⁠

References

Study Spotlight

https://www.theendobellycoach.com/podcast/new-endo-survey-study-review

https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2831953

Gluten and endo research

https://pmc.ncbi.nlm.nih.gov/articles/PMC7044830/

https://pmc.ncbi.nlm.nih.gov/articles/PMC12299565/#B89-medicina-61-01264

https://pubmed.ncbi.nlm.nih.gov/23334113/

https://www.fertstert.org/article/S0015-0282(11)01637-2/fulltext

https://pmc.ncbi.nlm.nih.gov/articles/PMC12299565/#B89-medicina-61-01264

https://pubmed.ncbi.nlm.nih.gov/39040659/

https://www.researchgate.net/publication/373663256_Diet_associations_in_endometriosis_a_critical_narrative_assessment_with_special_reference_to_gluten

Coeliac disease and endo

https://pubmed.ncbi.nlm.nih.gov/21840904/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601386/

https://www.siboinfo.com/associated-diseases.html

https://pubmed.ncbi.nlm.nih.gov/9660426/

https://www.coeliac.org.uk/information-and-support/coeliac-disease/coeliac-disease-faqs/

https://www.coeliac.org.uk/information-and-support/coeliac-disease/about-coeliac-disease/myths-about-coeliac-disease/?&&type=rfst&set=true#cookie-widget

https://www.beyondceliac.org/fast-facts-about-celiac-disease-infographic/

IBS

https://pmc.ncbi.nlm.nih.gov/articles/PMC9357916/

https://pmc.ncbi.nlm.nih.gov/articles/PMC11668458/

https://pubmed.ncbi.nlm.nih.gov/18715239/

https://pubmed.ncbi.nlm.nih.gov/28303579/

https://pubmed.ncbi.nlm.nih.gov/18715239/

https://www.youtube.com/watch?v=Sv8LjTgpmP0

https://www.ibssmart.com/sibo-symptoms-and-diagnosis

https://www.nature.com/articles/s41598-022-05933-1

https://www.msjonline.org/index.php/ijrms/article/view/15048

https://www.monashfodmap.com/about-fodmap-and-ibs/

https://pmc.ncbi.nlm.nih.gov/articles/PMC4918736/

https://pubmed.ncbi.nlm.nih.gov/28303579/

https://bmcwomenshealth.biomedcentral.com/articles/10.1186/s12905-025-03715-1

https://pmc.ncbi.nlm.nih.gov/articles/PMC12107219/

https://gut.bmj.com/content/71/9/1821

https://ift.onlinelibrary.wiley.com/doi/10.1111/1750-3841.70072

https://www.sciencedirect.com/science/article/pii/S2475299122121001#bib22

https://pmc.ncbi.nlm.nih.gov/articles/PMC10095554/

https://pmc.ncbi.nlm.nih.gov/articles/PMC9962481/

https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2024.1363455/full

Gliadin and intestinal permeability

https://pubmed.ncbi.nlm.nih.gov/16635908/

https://pubmed.ncbi.nlm.nih.gov/28123927/

https://pubmed.ncbi.nlm.nih.gov/30785904/

https://www.sciencedirect.com/science/article/pii/S2475299122121001#bib22

https://www.mdpi.com/2072-6643/7/3/1565#:~:text=5.,blind, placebo-controlled studies.

https://pubmed.ncbi.nlm.nih.gov/29202198/

https://pubmed.ncbi.nlm.nih.gov/16099460/

https://academic.oup.com/nutritionreviews/article-abstract/75/12/1046/4675264?redirectedFrom=fulltext&login=false

LPS translocation, leaky gut and endo

https://pmc.ncbi.nlm.nih.gov/articles/PMC7033038/

https://pmc.ncbi.nlm.nih.gov/articles/PMC12277312/

https://pmc.ncbi.nlm.nih.gov/articles/PMC9729346/

https://pmc.ncbi.nlm.nih.gov/articles/PMC12277312/

https://pmc.ncbi.nlm.nih.gov/articles/PMC10888589/

https://www.researchgate.net/publication/332701068_Lipopolysaccharide_promotes_early_endometrial-peritoneal_interactions_in_a_mouse_model_of_endometriosis

https://www.sciencedirect.com/science/article/pii/S0015028204012944

https://pubmed.ncbi.nlm.nih.gov/22109896/

https://bmcgastroenterol.biomedcentral.com/articles/10.1186/s12876-014-0189-7

https://integrativewomenshealthinstitute.com/leaky-gut-and-pelvic-pain/

https://pubmed.ncbi.nlm.nih.gov/19517230/

https://pubmed.ncbi.nlm.nih.gov/30430944/

https://pubmed.ncbi.nlm.nih.gov/29692669/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519769/

https://pubmed.ncbi.nlm.nih.gov/9660426/

https://genomemedicine.biomedcentral.com/articles/10.1186/s13073-016-0303-2

ATIs and inflammatory pathways

https://www.sciencedirect.com/science/article/pii/S2475299122121001#bib22

https://pubmed.ncbi.nlm.nih.gov/33928453/ - TLR4

https://pubmed.ncbi.nlm.nih.gov/30838396/ - CCL-2

https://www.sciencedirect.com/science/article/abs/pii/S1472648325000033 - CCL-2 and mast cells

https://www.sciencedirect.com/science/article/pii/S0015028211029335#:~:text=In addition to its role,-like benign disease, endometriosis. - CCL-2

https://pubmed.ncbi.nlm.nih.gov/36812343/ - IL-8

https://www.sciencedirect.com/science/article/abs/pii/S0198885923001131 - IL-8

https://pubmed.ncbi.nlm.nih.gov/11949939/ - IL-8

https://pubmed.ncbi.nlm.nih.gov/10690897/ - TNF-a

https://jmhg.springeropen.com/articles/10.1186/s43042-022-00285-x - TNF-a

https://pmc.ncbi.nlm.nih.gov/articles/PMC9265783/ - TNF-a

Produced by ⁠Chris Robson

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EP.371/ Study Spotlight: Can Lowering Gluten Intake Improve Pain and Quality of Life with Endometriosis?